For wrinkle treatment on the forehead (and “11’s) and around the eyes (“crow’s feet”), both Xeomin® and Botox® both are FDA-approved neurotoxin injections that work at the nerve-muscle interface to relax targeted muscles, helping patients achieve youthful facial rejuvenation without surgery or downtime. They work differently than other dermal fillers, such as Restylane or Radiesse, which work by filling lost volume. Instead of “filling” wrinkles, Xeomin and Botox relax targeted muscles in affected areas, offering the best wrinkle treatment available for the frown and forehead lines. These treatments target one of the underlying causes of frown lines and crow’s feet—the repeated muscle contractions from frowning and squinting over the years. When muscle activity is reduced you will begin to notice visible smoothing.